(19)
(11) EP 1 053 310 A1

(12)

(43) Date of publication:
22.11.2000 Bulletin 2000/47

(21) Application number: 99941243.0

(22) Date of filing: 20.08.1999
(51) International Patent Classification (IPC)7: C12N 15/00
(86) International application number:
PCT/US9919/030
(87) International publication number:
WO 0011/148 (02.03.2000 Gazette 2000/09)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

(30) Priority: 20.08.1998 US 96938 P
16.04.1999 US 293427
12.07.1999 US 143380 P

(71) Applicant: UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY
New Brunswick, NJ 08903 (US)

(72) Inventors:
  • FANG, Li
    New York, NY 10029 (US)
  • JIANG, Weining
    New York, NY 10021 (US)
  • MITTA, Masanori
    Tsuzuki-gun,Kyoto 610-03 (JP)
  • INOUYE, Masayori
    Piscataway, NY 08854 (US)
  • ETCHEGARAY, Jean-Pierre
    New Brunswick, NJ (US)
  • YAMANAKA, Kunitoshi
    Highland Park, NJ 08904 (US)

(74) Representative: Breese, Pierre 
Breese - Majerowicz3, avenue de l'Opéra
75001 Paris
75001 Paris (FR)

   


(54) COLD-SHOCK REGULATORY ELEMENTS, CONSTRUCTS THEREOF, AND METHODS OF USE