(19)

(11)

EP 1 053 344 A1

(12)

(43) Date of publication: 22.11.2000 Bulletin 2000/47 (21) Application number: 99901772.6 (22) Date of filing: 21.01.1999

(51) International Patent Classification (IPC)7: C12P 7/64, C12N 1/14 // C12P7:64, C12R1:645, C12N1:14, C12R1:645 (86) International application number: PCT/GB9900/211 (87) International publication number: WO 9940/215 (12.08.1999 Gazette 1999/32)

(84) Designated Contracting States: BE CH DE DK ES FR GB IE IT LI NL SE (30) Priority: 07.02.1998 GB 9802561 (71) Applicant: Avecia Limited Blackley, Manchester M9 8ZS (GB)	(72) Inventor: DUCHARS, Matthew Guy Billingham,Cleveland TS23 1YN (GB) (74) Representative: Revell, Christopher  Avecia LimitedIntellectual Property Group,PO Box 42,Hexagon House Blackley,Manchester, M9 8ZS Blackley,Manchester, M9 8ZS (GB)