(19)

(11)

EP 1 053 353 A1

(12)

(43) Date of publication: 22.11.2000 Bulletin 2000/47 (21) Application number: 99905618.7 (22) Date of filing: 02.02.1999

(51) International Patent Classification (IPC)7: C12Q 1/68, C12N 15/10, C07H 1/08 (86) International application number: PCT/US9902/190 (87) International publication number: WO 9939/010 (05.08.1999 Gazette 1999/31)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE (30) Priority: 02.02.1998 US 126413 P 02.02.1998 US 126429 P (71) Applicant: Gentra Systems Inc. Minneapolis, MN 55447 (US)	(72) Inventors: HEATH, Ellen, M. Minnetonka, MN 55305 (US) SHUMAN, Ruth, M. Minnetonka, MN 55305 (US) (74) Representative: Chapman, Paul William et al Kilburn & Strode,20 Red Lion Street London WC1R 4PJ London WC1R 4PJ (GB)