N-HYDROXY-2-(ALKYL, ARYL, OR HETEROARYL SULFANYL, SULFINYL OR SULFONYL)-3-SUBSTITUTED-ALKYL, ARYL OR HETEROARYLAMIDES AS MATRIX METALLOPROTEINASE INHIBITORS - Patent 1054858

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EP 1 054 858 A1

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(43)	Date of publication:
	29.11.2000 Bulletin 2000/48

(21)	Application number: 98943392.5

(22)	Date of filing: 26.08.1998

(51)	International Patent Classification (IPC)⁷: C07C 239/14, C07D 211/20, C07D 241/04, A61K 31/16

(86)	International application number:
	PCT/US9817/633

(87)	International publication number:
	WO 9942/436 (26.08.1999 Gazette 1999/34)

(84)	Designated Contracting States:
	AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU NL PT SE
	Designated Extension States:
	AL LT LV RO SI

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Priority:

19.02.1998 US 26372

(71)	Applicant: American Cyanamid Company
	Madison,New Jersey 07940-0874 (US)

(72)	Inventors:
	VENKATESAN, Aranapakam, Mudumbai Rego Park, NY 11374 (US) GROSU, George, Theodore Pearl River, NY 10965 (US) DAVIS, Jamie, Marie Nyack, NY 10960 (US) BAKER, Jannie, Lea White Plains, NY 10607 (US) LEVIN, Jeremy, Ian New City, New York 10956 (US)

(74)	Representative: Talbott, Dawn Jacqueline
	Wyeth Laboratories,Patent Department,Huntercombe Lane South,Taplow Maidenhead,Berkshire SL6 0PH Maidenhead,Berkshire SL6 0PH (GB)

(54)	N-HYDROXY-2-(ALKYL, ARYL, OR HETEROARYL SULFANYL, SULFINYL OR SULFONYL)-3-SUBSTITUTED-ALKYL, ARYL OR HETEROARYLAMIDES AS MATRIX METALLOPROTEINASE INHIBITORS