(19)

(11)

EP 1 054 961 A2

(12)

(88) Date of publication A3: 23.09.1999 (43) Date of publication: 29.11.2000 Bulletin 2000/48 (21) Application number: 99905816.7 (22) Date of filing: 05.02.1999

(51) International Patent Classification (IPC)7: C12N 15/12, C12N 5/10, C07K 14/705, C07K 14/28, A61K 38/17, C12Q 1/68 // G01N33:50 (86) International application number: PCT/US9902/570 (87) International publication number: WO 9941/374 (19.08.1999 Gazette 1999/33)

(84) Designated Contracting States: BE DE ES FR GB IT NL (30) Priority: 17.02.1998 US 24808 (71) Applicant: INCYTE PHARMACEUTICALS, INC. Palo Alto, CA 94304 (US)	(72) Inventors: TANG, Y., Tom San Jose, CA 95118 (US) CORLEY, Neil, C. Mountain View, CA 94040 (US) LAL, Preeti Santa Clara, CA 95054 (US) (74) Representative: Wright, Simon Mark et al J.A. Kemp & Co.14 South SquareGray's Inn London WC1R 5LX London WC1R 5LX (GB)