(19)
(11) EP 1 058 729 A1

(12)

(43) Date of publication:
13.12.2000 Bulletin 2000/50

(21) Application number: 99911099.2

(22) Date of filing: 03.03.1999
(51) International Patent Classification (IPC)7C12N 15/12, C12N 15/62, C12N 15/85, C12N 15/11, C12N 5/10, C12N 5/12, C12Q 1/68, A61K 39/395, A61K 48/00, A61K 38/17
(86) International application number:
PCT/US9904/740
(87) International publication number:
WO 9945/113 (10.09.1999 Gazette 1999/36)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

(30) Priority: 03.03.1998 US 76942 P

(71) Applicant: LUDWIG INSTITUTE FOR CANCER RESEARCH
New York, NY 10158 (US)

(72) Inventors:
  • JONK, Luigi, J., C.
    NL-9750 AA Haren (NL)
  • ITOH, Susumo
    S-751 24 Uppsala (SE)
  • HELDIN, Carl-Henrik
    S-751 24 Uppsala (SE)
  • TEN DIJKE, Peter
    S-751 24 Uppsala (SE)
  • KRUIJER, Wiebe
    NL-9750 AA Haren (NL)

(74) Representative: Hughes, Siân Victoria et al
Venner, Shipley & Co20 Little Britain
London EC1A 7DH
London EC1A 7DH (GB)

   


(54) SMAD BINDING ELEMENTS AND USES THEREOF