(19)
(11) EP 1 058 736 A1

(12)

(43) Date of publication:
13.12.2000 Bulletin 2000/50

(21) Application number: 99908422.1

(22) Date of filing: 24.02.1999
(51) International Patent Classification (IPC)7C12Q 1/00
(86) International application number:
PCT/US9904/011
(87) International publication number:
WO 9942/607 (26.08.1999 Gazette 1999/34)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

(30) Priority: 24.02.1998 US 75596 P

(71) Applicants:
  • UNIVERSITY OF NOTRE DAME DU LAC
    Notre Dame, IN 46556 (US)
  • Juni, Jack Edward
    Royal Oak, MI 48067 (US)

(72) Inventors:
  • JUNI, Jack, Edward
    Royal Oak, MI 48067 (US)
  • SAZ, Howard, J.
    South Bend, IN 46635 (US)
  • DEBRUYN, Becky, S.
    Granger, IN 46530 (US)

(74) Representative: Hay, Martin Alexander 
Martin A. Hay & Co.13 Queen Victoria Street
MacclesfieldCheshire SK11 6LP
MacclesfieldCheshire SK11 6LP (GB)

   


(54) USE OF SUCCINATE AS A DIAGNOSTIC TOOL