(19)
(11) EP 1 061 926 A2

(12)

(88) Date of publication A3:
11.11.1999

(43) Date of publication:
27.12.2000 Bulletin 2000/52

(21) Application number: 99909233.1

(22) Date of filing: 18.03.1999
(51) International Patent Classification (IPC)7: A61K 31/55, A61K 31/435, C07D 471/14, C07D 498/04, C07D 471/04, C07D 487/04
(86) International application number:
PCT/JP9901/358
(87) International publication number:
WO 9947/132 (23.09.1999 Gazette 1999/38)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

(30) Priority: 19.03.1998 JP 6999998

(71) Applicant: Takeda Chemical Industries, Ltd.
Osaka-shi,Osaka 541-0045 (JP)

(72) Inventors:
  • NATSUGARI, Hideaki
    Ashiya-shiHyogo 659-0042 (JP)
  • DOI, Takayuki
    Izumi-shiOsaka 594-0013 (JP)
  • IKEURA, Yoshinori
    Kashiba-shiNara 639-0251 (JP)

(74) Representative: von Kreisler, Alek, Dipl.-Chem. et al
Patentanwälte,von Kreisler-Selting-Werner,Bahnhofsvorplatz 1 (Deichmannhaus)
50667 Köln
50667 Köln (DE)

   


(54) HETEROCYCLIC COMPOUNDS, THEIR PRODUCTION AND USE AS TACHYKININ RECEPTOR ANTAGONISTS