(19)
(11) EP 1 062 205 A2

(12)

(88) Date of publication A3:
28.10.1999

(43) Date of publication:
27.12.2000 Bulletin 2000/52

(21) Application number: 99908378.5

(22) Date of filing: 24.02.1999
(51) International Patent Classification (IPC)7: C07D 209/18, C07D 209/22, C07D 491/04, C07D 401/04, C07D 417/12, C07D 413/12, C07D 403/12, C07D 209/12, C07D 209/14, C07D 403/06, C07D 409/04, C07D 403/10
// (C07D491/04, 317:00), C07D209:00,(C07D401/04, 213:00), C07D209:00,(C07D417/12, 285:00), C07D209:00,(C07D413/12, 263:00), C07D209:00, C07D403:12
(86) International application number:
PCT/US9903/898
(87) International publication number:
WO 9943/654 (02.09.1999 Gazette 1999/35)
(84) Designated Contracting States:
AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE

(30) Priority: 25.02.1998 US 30592

(71) Applicant: GENETICS INSTITUTE, INC.
Cambridge,Massachusetts 02140 (US)

(72) Inventors:
  • SEEHRA, Jasbir, S.
    Lexington, MA 02173 (US)
  • MCKEW, John, C.
    Arlington, MA 02474 (US)
  • LOVERING, Frank
    Acton, MA 01720 (US)
  • BEMIS, Jean, E.
    Arlington, MA 02174 (US)
  • XIANG, YiBin
    Acton, MA 01720 (US)
  • CHEN, Lihren
    Cambridge, MA 02140 (US)
  • KNOPF, John, L.
    Acton, MA 01720 (US)

(74) Representative: Wileman, David Francis, Dr. 
c/o Wyeth LaboratoriesHuntercombe Lane South
TaplowMaidenheadBerkshire SL6 OPH
TaplowMaidenheadBerkshire SL6 OPH (GB)

   


(54) INHIBITORS OF PHOSPHOLIPASE ENZYMES