(19)

(11)

EP 1 062 316 A1

(12)

(43) Date of publication: 27.12.2000 Bulletin 2000/52 (21) Application number: 00902394.6 (22) Date of filing: 12.01.2000

(51) International Patent Classification (IPC)7: C12M 1/02 (86) International application number: PCT/US0000/736 (87) International publication number: WO 0042/164 (20.07.2000 Gazette 2000/29)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE (30) Priority: 12.01.1999 US 115736 P 17.09.1999 US 398573 17.09.1999 WO PCT/US99/21657 19.11.1999 US 166452 P 14.12.1999 US 170566 P (71) Applicant: Kerouac, Paul E. Hollis, NH 03049 (US)	(72) Inventor: Kerouac, Paul E. Hollis, NH 03049 (US) (74) Representative: McCarthy, Denis Alexis et al MacLachlan & Donaldson47 Merrion Square Dublin 2 Dublin 2 (IE)