(19)
(11) EP 1 063 986 A1

(12)

(43) Date of publication:
03.01.2001 Bulletin 2001/01

(21) Application number: 99908466.8

(22) Date of filing: 25.02.1999
(51) International Patent Classification (IPC)7: A61K 31/28, A61K 31/315, A61K 31/505, C07D 239/545, C07D 403/12, C07D 495/04
(86) International application number:
PCT/US9904/114
(87) International publication number:
WO 9943/313 (02.09.1999 Gazette 1999/35)
(84) Designated Contracting States:
AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

(30) Priority: 25.02.1998 US 75873 P

(71) Applicants:
  • Therex Technologies, Inc.
    West Amherst, NY 14288 (US)
  • THE RESEARCH FOUNDATION OFSTATE UNIVERSITY OF NEW YORK
    Albany,New York 12201-0009 (US)

(72) Inventors:
  • DUNN, Joseph, A.
    Amherst, NY 14221 (US)
  • BARDOS, Thomas, J.
    Snyder, NY 14226 (US)
  • KUNG, Hank, F.
    Wynnewood, PA 19096 (US)

(74) Representative: Dall'Olio, Giancarlo 
c/o INVENTION s.a.s.,Via delle Armi, 1
40137 Bologna
40137 Bologna (IT)

   


(54) COMPOUNDS AND METHODS FOR USE IN TREATING NEOPLASIA, CANCER, HYPERPROLIFERATIVE CELL GROWTH AND CHRONIC INFLAMMATORY DISEASES