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(11)

EP 1 064 033 A1

(12)

(43) Date of publication: 03.01.2001 Bulletin 2001/01 (21) Application number: 99911453.1 (22) Date of filing: 17.03.1999

(51) International Patent Classification (IPC)7: A61L 31/00, A61L 27/00 (86) International application number: PCT/US9905/847 (87) International publication number: WO 9947/188 (23.09.1999 Gazette 1999/38)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE (30) Priority: 17.03.1998 US 42549 16.11.1998 US 192988 (71) Applicant: TISSUE ENGINEERING, INC. Boston, MA 02210 (US)	(72) Inventors: BELL, Eugene Boston, MA 02215 (US) SIOUSSAT, Tracy, M. Reading, MA 02026 (US) BEGLEY, Michael, J. Somerville, MA 02143 (US) (74) Representative: Lock, Graham James et al Fry Heath & Spence,The Old College,53 High Street Horley,Surrey RH6 7BN Horley,Surrey RH6 7BN (GB)