(19)
(11) EP 1 064 265 B8

(12) CORRECTED EUROPEAN PATENT SPECIFICATION
Note: Bibliography reflects the latest situation

(15) Correction information:
Corrected version no 1 (W1 B1)

(48) Corrigendum issued on:
13.10.2004 Bulletin 2004/42

(45) Mention of the grant of the patent:
14.04.2004 Bulletin 2004/16

(21) Application number: 00902349.0

(22) Date of filing: 06.01.2000
(51) International Patent Classification (IPC)7: C07D 213/73, C07D 213/12
(86) International application number:
PCT/US2000/000332
(87) International publication number:
WO 2000/043365 (27.07.2000 Gazette 2000/30)

(54)

SYNTHESIS OF 3-AMINO-2-CHLORO-4-METHYLPYRIDINE FROM MALONONITRILE AND ACETONE

SYNTHESE VON 3-AMINO-2-CHLOR-4-METHYLPYRIDIN AUS MALONONITRIL UND ACETON

SYNTHESE DE 3-AMINO-2-CHLORO-4-METHYLPYRIDINE A PARTIR DE MALONONITRILE ET D'ACETONE

(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

(30) Priority: 22.01.1999 US 116704 P

(43) Date of publication of application:
03.01.2001 Bulletin 2001/01

(73) Proprietor: BOEHRINGER INGELHEIM PHARMACEUTICALS INC.
Ridgefield, Connecticut 06877-0368 (US)

(72) Inventor:
  • GROZINGER, Karl
    Ridgefield, CT 06877 (US)

(74) Representative: Laudien, Dieter, Dr. 
c/o Boehringer Ingelheim GmbH
55216 Ingelheim
55216 Ingelheim (DE)


(56) References cited: : 
US-A- 5 654 429
US-A- 5 686 618
 US-A- 5 668 287
   
  • EGE GÜNTER ET AL.: SYNTHESIS, vol. 5, 1979, pages 376-378, XP001109375 STUTTGART DE
  • ZHANG T Y ET AL: "Regioselective Synthesis of 2-Chloro-3-Pyridinecarboxylates" TETRAHEDRON, ELSEVIER SCIENCE PUBLISHERS, AMSTERDAM, NL, vol. 51, no. 48, 1 November 1995 (1995-11-01), pages 13177-13184, XP004104612 ISSN: 0040-4020
   
Note: Within nine months from the publication of the mention of the grant of the European patent, any person may give notice to the European Patent Office of opposition to the European patent granted. Notice of opposition shall be filed in a written reasoned statement. It shall not be deemed to have been filed until the opposition fee has been paid. (Art. 99(1) European Patent Convention).