(19)
(11) EP 1 064 394 B8

(12) CORRECTED EUROPEAN PATENT SPECIFICATION
Note: Bibliography reflects the latest situation

(15) Correction information:
Corrected version no 1 (W1 B1)

(48) Corrigendum issued on:
30.03.2005 Bulletin 2005/13

(45) Mention of the grant of the patent:
02.02.2005 Bulletin 2005/05

(21) Application number: 99917833.8

(22) Date of filing: 22.03.1999
(51) International Patent Classification (IPC)7C12N 15/87, C12Q 1/68, A01K 67/033, C12N 15/00
(86) International application number:
PCT/EP1999/001903
(87) International publication number:
WO 1999/049066 (30.09.1999 Gazette 1999/39)

(54)

METHOD FOR BALLISTIC TRANSFORMATION OF CAENORHABDITIS ELEGANS

VERFAHREN ZUR BALLISTISCHEN TRANSFORMATION VON CAENORHABDITIS ELEGANS

METHODE DE TRANSFORMATION BALISTIQUE DE CAENORHABDITIS ELEGANS


(84) Designated Contracting States:
BE CH DE FR GB LI LU NL

(30) Priority: 23.03.1998 GB 9806211
11.09.1998 GB 9819868

(43) Date of publication of application:
03.01.2001 Bulletin 2001/01

(73) Proprietor: Devgen NV
9052 Gent-Zwijnaarde (BE)

(72) Inventor:
  • Schnabel, Ralf
    38118 Braunschweig (DE)

(74) Representative: Baldock, Sharon Claire et al
BOULT WADE TENNANT, Verulam Gardens 70 Gray's Inn Road
London WC1X 8BT
London WC1X 8BT (GB)


(56) References cited: : 
WO-A-93/24626
   
  • HARRINGTON ET AL: "DNA transformation using electrically charged tungsten microelectrodes" PROC. SOUTH. BIOMED. ENG. CONF., 14TH (1995), 12-15 PUBLISHER: INSTITUTE OF ELECTRICAL AND ELECTRONICS ENGINEERS, NEW YORK, N. Y., XP002109318
  • MELLO ET AL: "Efficient gene transfer in C. elegans: extrachromosomal maintenance and integration of transforming sequences" EMBO JOURNAL, vol. 10, no. 12, 1991, pages 3959-3970, XP002109319 cited in the application
  • GRANATO ET AL: "pha-1, a selectable marker for gene transfer in C. elegans" NUCLEIC ACIDS RESEARCH, vol. 22, no. 9, 1994, pages 1762-1763, XP002109320 cited in the application
  • HASHMI ET AL: "GFP: green fluorescent protein a versatile gene marker for entomopathogenic nematodes" FUNDAMENTAL AND APPLIED NEMATOLOGY, vol. 20, no. 4, 1 January 1997 (1997-01-01), pages 323-327, XP000749597
  • KLEIN ET AL: "Transformation of microbes, plants and animals by particle bombardment" BIO/TECHNOLOGY, vol. 10, March 1992 (1992-03), pages 286-291, XP002109321 cited in the application
  • WILM T ET AL: "Ballistic transformation of Caenorhabditis elegans" GENE: AN INTERNATIONAL JOURNAL ON GENES AND GENOMES, vol. 229, no. 1-2, 18 March 1999 (1999-03-18), page 31-35 XP004161155
   
Note: Within nine months from the publication of the mention of the grant of the European patent, any person may give notice to the European Patent Office of opposition to the European patent granted. Notice of opposition shall be filed in a written reasoned statement. It shall not be deemed to have been filed until the opposition fee has been paid. (Art. 99(1) European Patent Convention).