(19)

(11)

EP 1 066 524 A1

(12)

(43) Date of publication: 10.01.2001 Bulletin 2001/02 (21) Application number: 99911547.0 (22) Date of filing: 31.03.1999

(51) International Patent Classification (IPC)7: G01N 33/564, G01N 33/68, C07K 14/47 (86) International application number: PCT/CA9900/277 (87) International publication number: WO 9951/987 (14.10.1999 Gazette 1999/41)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE (30) Priority: 01.04.1998 CA 2233706 (71) Applicant: McGILL UNIVERSITY Montreal,Québéc H3A 2T5 (CA)	(72) Inventors: ANTEL, Jack, P. Westmount, Québec H3Y 2W3 (CA) PRAT, Alexandre Outremont, Québec H2V 3J8 (CA) (74) Representative: Jacob, Reuben Ellis et al Edward Evans & Co.,Clifford's Inn,Fetter Lane London EC4A 1BX London EC4A 1BX (GB)