(19)
(11) EP 1 068 190 A1

(12)

(43) Date of publication:
17.01.2001 Bulletin 2001/03

(21) Application number: 98963961.2

(22) Date of filing: 15.12.1998
(51) International Patent Classification (IPC)7C07D 241/44, A61K 31/50
(86) International application number:
PCT/US9826/704
(87) International publication number:
WO 9950/254 (07.10.1999 Gazette 1999/40)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
Designated Extension States:
AL LT LV MK RO SI

(30) Priority: 31.03.1998 US 80042 P

(71) Applicant: WARNER-LAMBERT COMPANY
Morris PlainsNew Jersey 07950 (US)

(72) Inventors:
  • DUDLEY, Danette, Andrea
    Ann Arbor, MI 48105 (US)
  • EDMUNDS, Jeremy, John
    Ypsilanti, MI 48197 (US)

(74) Representative: Tesch, Rudolf, Dr. et al
Warner-Lambert Company,Legal Division,Patent Department,c/o Gödecke AG,Mooswaldallee 1
79090 Freiburg
79090 Freiburg (DE)

   


(54) QUINOXALINONES AS SERINE PROTEASE INHIBITORS SUCH AS FACTOR XA AND THROMBIN