BENZYLPIPERAZINYL- AND BENZYLPIPERIDINYL ETHANONE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS DOPAMINE D 4? RECEPTOR ANTAGONISTS - Patent 1068193

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EP 1 068 193 A1

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(43)	Date of publication:
	17.01.2001 Bulletin 2001/03

(21)	Application number: 99909657.1

(22)	Date of filing: 26.02.1999

(51)	International Patent Classification (IPC)⁷: C07D 401/06, A61K 31/445, C07D 295/14, A61K 31/495, C07D 209/08, C07D 215/08, C07D 265/36, A61K 31/535, C07D 279/16, A61K 31/54, C07D 209/54

(86)	International application number:
	PCT/US9904/309

(87)	International publication number:
	WO 9943/670 (02.09.1999 Gazette 1999/35)

(84)	Designated Contracting States:
	AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
	Designated Extension States:
	AL LT LV MK RO SI

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Priority:

26.02.1998 US 30987

(71)	Applicant: NEUROGEN CORPORATION
	Branford, CT 06405 (US)

(72)	Inventors:
	KOVER, Renata, X. 22470-220 Rio de Janeiro, RJ (BR) TERDJANIAN, Silva New Britain, CT 06053 (US) TRAN, Jennifer Guilford, CT 06437 (US) THURKAUF, Andrew Danbury, CT 06811 (US)

(74)	Representative: Eyles, Christopher Thomas et al
	W.P. THOMPSON & CO.Celcon House289-293 High Holborn London WC1V 7HU London WC1V 7HU (GB)

(54)	BENZYLPIPERAZINYL- AND BENZYLPIPERIDINYL ETHANONE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS DOPAMINE D 4? RECEPTOR ANTAGONISTS