(19)
(11) EP 1 068 304 A1

(12)

(43) Date of publication:
17.01.2001 Bulletin 2001/03

(21) Application number: 99916517.8

(22) Date of filing: 08.04.1999
(51) International Patent Classification (IPC)7C12N 9/99, C12N 9/48, A01N 43/78, A01N 37/18, A01N 33/26, C07D 413/00, C07D 401/00, C07D 277/60, C07C 241/00
(86) International application number:
PCT/US9907/723
(87) International publication number:
WO 9953/039 (21.10.1999 Gazette 1999/42)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
Designated Extension States:
SI

(30) Priority: 09.04.1998 US 81221 P

(71) Applicant: SMITHKLINE BEECHAM CORPORATION
PhiladelphiaPennsylvania 19103 (US)

(72) Inventors:
  • THOMPSON, Scott, Kevin
    Wayne, PA 19087 (US)
  • VEBER, Daniel, Frank
    Ambler, PA 19002 (US)
  • TOMASZEK, Thaddeus, Anthony
    Collegeville, PA 19426 (US)
  • TEW, David, Graham
    Audubon, PA 19403 (US)

(74) Representative: Rutter, Keith, Dr. et al
SmithKline Beecham plcCorporate Intellectual Property,Two New Horizons Court
Brentford, Middlesex TW8 9EP
Brentford, Middlesex TW8 9EP (GB)

   


(54) TREATMENT OF PARASITIC DISEASES BY INHIBITION OF CYSTEINE PROTEASES OF THE PAPAIN SUPERFAMILY