(19)
(11) EP 1 068 356 B8

(12) CORRECTED EUROPEAN PATENT SPECIFICATION
Note: Bibliography reflects the latest situation

(15) Correction information:
Corrected version no 1 (W1 B1)

(48) Corrigendum issued on:
03.01.2007 Bulletin 2007/01

(45) Mention of the grant of the patent:
27.09.2006 Bulletin 2006/39

(21) Application number: 99916283.7

(22) Date of filing: 31.03.1999
(51) International Patent Classification (IPC): 
C12Q 1/68(2006.01)
(86) International application number:
PCT/US1999/007203
(87) International publication number:
WO 1999/051773 (14.10.1999 Gazette 1999/41)

(54)

ADDRESSABLE PROTEIN ARRAYS

ADRESSIERBARE PROTEIN ARRAYS

SYSTEMES DE PROTEINES ADRESSABLES


(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

(30) Priority: 03.04.1998 US 80686 P

(43) Date of publication of application:
17.01.2001 Bulletin 2001/03

(73) Proprietor: Adnexus Therapeutics, Inc.
Waltham MA 02453 (US)

(72) Inventors:
  • KUIMELIS, Robert, G.
    Brighton, MA 02135 (US)
  • WAGNER, Richard
    Concord, MA 01742 (US)

(74) Representative: Schnappauf, Georg et al
Dr. Volker Vossius Patent- und Rechtsanwaltskanzlei Geibelstrasse 6
81679 München
81679 München (DE)


(56) References cited: : 
WO-A-92/10092
WO-A1-92/10588
WO-A1-98/31700
US-A- 5 556 752
WO-A1-00/22172
WO-A1-93/03172
US-A- 5 545 531
   
  • ROBERTS AND SZOSTAK: "RNA-peptide fusions for the in vitro selection of peptides and proteins" PROC. NATL. ACAD. SCI. USA, vol. 94, November 1997 (1997-11), pages 12297-12302, XP002913434
  • LIPSHUTZ ET AL.: "Using Oligonucleotide Probe Arrays To Access Genetic diversity" BIOTECHNIQUES, vol. 19, no. 3, September 1995 (1995-09), pages 442-447, XP000541924
  • PEASE ET AL.: "Light-generated oligonucleotide arrays for rapid DNA sequence analysis" PROC. NATL. ACAD. SCI. USA, vol. 91, May 1994 (1994-05), pages 5022-5026, XP000196311
  • RAYNAUD ET AL.: "Synthesis and Characterization of O6-Modified Deoxyguanosine-Containing Oligodeoxyribonucleotides for Triple-Helix Formation" TETRAHEDRON, vol. 52, no. 6, 1996, pages 2047-2064, XP004104436
  • MASKOS U. et al., "Parallel Analysis of Oligodeoxyribonucleotide Interactions. I. Analysis of Factors Influencing Oligonucleotides Duplex Formation", NUCLEIC ACIDS RESEARCH, 1992, Vol. 20, No. 7, pages 1675-1678, XP002921407
  • GUO Z. et al., "Direct Fluorescence Analysis of Genetic Polymorphisms by hybridization with Oligonucleotide Arrays on Glass Supports", NUCLEIC ACIDS RESEARCH, 1994, Vol. 22, No. 24, pages 5456-5465, XP002006248
  • MASKOS U. ET AL: 'Oligonucleotide hybridizations on glass supports: a novel linker for oligonucleotide synthesis and hybridsation properties of oligonucleotides synthesized in situ' NUCLEIC ACIDS RESEARCH vol. 20, no. 7, pages 1679 - 1684
  • SLOMKOWSKI S. ET AL: 'Two-dimensional Latex Assemblies and their potential application in diagnostics' TRENDS IN POLYMER SCIENCE vol. 3, no. 9, pages 297 - 304
  • NIEMEYER C. ET AL: 'Oligonucleotide-directed self-assembly of proteins: semisynthetic DNA-streptavidin hybrid molecules as connectors for the generation of macroscopic arrays and the construction of supramolecular bioconjugates' NUCLEIC ACIDS RESEARCH vol. 22, no. 25, 1994, pages 5530 - 5539
   
Note: Within nine months from the publication of the mention of the grant of the European patent, any person may give notice to the European Patent Office of opposition to the European patent granted. Notice of opposition shall be filed in a written reasoned statement. It shall not be deemed to have been filed until the opposition fee has been paid. (Art. 99(1) European Patent Convention).