(19)

(11)

EP 1 071 781 A1

(12)

(43) Date of publication: 31.01.2001 Bulletin 2001/05 (21) Application number: 99916442.9 (22) Date of filing: 06.04.1999

(51) International Patent Classification (IPC)7: C12N 15/19, C12N 5/10, C07K 14/52, C07K 16/24, A61K 38/19 (86) International application number: PCT/US9907/592 (87) International publication number: WO 9954/469 (28.10.1999 Gazette 1999/43)

(84) Designated Contracting States: BE DE ES FR GB IT NL (30) Priority: 20.04.1998 US 63623 (71) Applicant: INCYTE PHARMACEUTICALS, INC. Palo Alto, CA 94304 (US)	(72) Inventors: TANG, Y., Tom San Jose, CA 95118 (US) CORLEY, Neil, C. Mountain View, CA 94040 (US) BAUGHN, Mariah San Leandro, CA 94577 (US) (74) Representative: Wright, Simon Mark et al J.A. Kemp & Co.14 South SquareGray's Inn London WC1R 5LX London WC1R 5LX (GB)