(19)
(11) EP 1 071 811 B8

(12) CORRECTED EUROPEAN PATENT SPECIFICATION
Note: Bibliography reflects the latest situation

(15) Correction information:
Corrected version no 1 (W1 B1)

(48) Corrigendum issued on:
02.01.2003 Bulletin 2003/01

(45) Mention of the grant of the patent:
06.03.2002 Bulletin 2002/10

(21) Application number: 98917568.2

(22) Date of filing: 22.04.1998
(51) International Patent Classification (IPC)7: C12Q 1/68
(86) International application number:
PCT/IE9800/030
(87) International publication number:
WO 9905/4501 (28.10.1999 Gazette 1999/43)

(54)

A METHOD FOR THE CHARACTERISATION OF NUCLEIC ACID MOLECULES INVOLVING GENERATION OF EXTENDIBLE UPSTREAM DNA FRAGMENTS RESULTING FROM THE CLEAVAGE OF NUCLEIC ACID AT AN ABASIC SITE

VERFAHREN ZUR CHARAKTERISIERUNG VON NUKLEINSÄUREMOLEKULEN, DAS DIE ERZEUGUNG VON VERLÄNGERBAREN AUFWÄRTSGELEGENEN DNS-FRAGMENTEN, DIE DURCH SPALTUNG DER NUKLEINSÄURE AN EINER ABASISCHEN STELLE ENTSTEHT, UMFASST

METHODE DE CARACTERISATION DE MOLECULES D'ACIDE NUCLEIQUE IMPLIQUANT LA GENERATION DE FRAGMENTS D'ADN D'AMONT EXTENSIBLES A PARTIR DU CLIVAGE D'ACIDE NUCLEIQUE AU NIVEAU D'UN SITE ABASIQUE

(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

(43) Date of publication of application:
31.01.2001 Bulletin 2001/05

(73) Proprietors:
  • Enterprise Ireland (trading as BioResearch Ireland)
    Dublin 9 (IE)
  • University College Cork-National University of Ireland, Cork
    Cork (IE)

(72) Inventors:
  • McCARTHY, Thomas, Valentine
    Cork (IE)
  • VAUGHAN, Patrick, Martin
    Cork (IE)

(74) Representative: Ryan, Anne Mary et al
c/o Anne Ryan & Co. 60 Northumberland Road
Ballsbridge Dublin 4
Ballsbridge Dublin 4 (IE)


(56) References cited: : 
WO-A-96/30545
WO-A-97/12061
 WO-A-97/03210
   
  • VAUGHAN P ET AL: "A novel process for mutation detection using uracil DNA-glycosylase" NUCLEIC ACIDS RESEARCH, vol. 26, no. 12, February 1998, pages 810-15, XP002088826
  • MCGRATH A ET AL: "A DNA glycolase-based fingerprint for accurate identification of amplified DNA products and its application in the accurate diagnosis of infectiuos organisms" ANALYTICAL BIOCHEMISTRY, vol. 259, no. 2, - June 1998 pages 288-92, XP002088827
   
Note: Within nine months from the publication of the mention of the grant of the European patent, any person may give notice to the European Patent Office of opposition to the European patent granted. Notice of opposition shall be filed in a written reasoned statement. It shall not be deemed to have been filed until the opposition fee has been paid. (Art. 99(1) European Patent Convention).