(19)

(11)

EP 1 075 269 A2

(12)

(88) Date of publication A3: 06.01.2000 (43) Date of publication: 14.02.2001 Bulletin 2001/07 (21) Application number: 99921785.4 (22) Date of filing: 07.05.1999

(51) International Patent Classification (IPC)7: A61K 35/54 (86) International application number: PCT/US9910/049 (87) International publication number: WO 9958/133 (18.11.1999 Gazette 1999/46)

(84) Designated Contracting States: DE ES FR GB IE IT (30) Priority: 08.05.1998 US 84765 P (71) Applicant: DCV, Inc. Wilmington,Delaware 19810 (US)	(72) Inventors: GREENBLATT, Hellen, Chaya Wilmington, DE 19808 (US) ADALSTEINSSON, Orn Kennett Square, PA 19348 (US) BRODIE, David, A. East Windsor, NJ 08520 (US) JACOBY, Hank Brigantine, NJ 08522 (US) (74) Representative: Jones, Alan John et al CARPMAELS & RANSFORD43 Bloomsbury Square London, WC1A 2RA London, WC1A 2RA (GB)