| (84) |
Designated Contracting States: |
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AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE |
| (30) |
Priority: |
08.05.1998 AU PP344598
|
| (43) |
Date of publication of application: |
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14.02.2001 Bulletin 2001/07 |
| (60) |
Divisional application: |
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10151958.5 |
| (73) |
Proprietor: Cephalon Australia (VIC) Pty Ltd. |
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Macquarie Park NSW 2113 (AU) |
|
| (72) |
Inventors: |
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- COIA, Gregory
Brunswick, VIC 3056 (AU)
- HUDSON, Peter, John
Blackburn, VIC 3130 (AU)
- ILIADES, Peter
North Balwyn, VIC 3104 (AU)
- IRVING, Robert, Alexander
Mulgrave, VIC 3170 (AU)
|
| (74) |
Representative: Elsy, David et al |
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Withers & Rogers LLP
Goldings House
2 Hays Lane
London SE1 2HW
2 Hays Lane
London SE1 2HW (GB) |
| (56) |
References cited: :
WO-A-94/06928
US-A- 5 643 768
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US-A- 5 602 001
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- HANES J & PLÜCKTHUN A: "In vitro selection and evolution of functional proteins by
using ribosome display" PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, NATIONAL
ACADEMY OF SCIENCE. WASHINGTON, US, no. 94, pages 4937-4942, XP002077149 ISSN: 0027-8424
- LIZARDI P M ET AL: "EXPONENTIAL AMPLIFICATION OF RECOMBINANT-RNA HYBRIDIZATION PROBES"
BIO/TECHNOLOGY, NATURE PUBLISHING CO. NEW YORK, US, vol. 6, 1 October 1988 (1988-10-01),
pages 1197-1202, XP000647526 ISSN: 0733-222X
- PROC. NATL. ACAD. SCI. U.S.A., 93, (1996), BROWN D. and GOLD L., "RNA Replication
by Qbeta Replicase: A Working Model", pages 11558-11562.
- J. BIOL. CHEM., 269(2), (1994), RYABOVA L. et al., "Coupled Replication-Translation
of Amplifiable Messenger RNA", pages 1501-1505.
- PROC. NATL. ACAD. SCI. U.S.A., 90, (1993), MOROZOV I.Y. et al., "Synergism in Replication
and Translation of Messenger RNA in a Cell-Free System", pages 9325-9329.
- J. MOL. BIOL., 249, (1995), ROHDE N. et al., "The Mutant Distribution of an RNA Species
Replicated by Qbeta Replicase", pages 756-762.
- BIOPHYS. CHEM., 66, (1997), BIEBRICHER C.K. and GARDINER W.C., "Molecular Evolution
of RNA In Vitro", pages 179-192.
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