(19)
(11) EP 1 077 708 A1

(12)

(43) Date of publication:
28.02.2001 Bulletin 2001/09

(21) Application number: 99921705.2

(22) Date of filing: 06.05.1999
(51) International Patent Classification (IPC)7: A61K 31/70
(86) International application number:
PCT/US9909/863
(87) International publication number:
WO 9956/755 (11.11.1999 Gazette 1999/45)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

(30) Priority: 06.05.1998 US 84512 P

(71) Applicants:
  • UNIVERSITY OF IOWA RESEARCH FOUNDATION
    Iowa City, IA 52242 (US)
  • Ottawa Civic Loeb Research Institute
    Ottawa,Ontario K1Y 4E9 (CA)
  • The United States of America as represented by The Secretary of the Navy
    Washington, DC 20350-1000 (US)

(72) Inventors:
  • GRAMZINSKI, Robert, A.
    Rockville, MD 20805 (US)
  • KRIEG, Arthur, M.
    Iowa City, IA 52246 (US)
  • DAVIS, Heather, L.
    Ottawa, Ontario K1Y 4E9 (CA)
  • HOFFMAN, Stephen, L.
    Gaithersburg, MD 20878 (US)

(74) Representative: Jump, Timothy John Simon et al
Venner Shipley & Co.20 Little Britain
London EC1A 7DH
London EC1A 7DH (GB)

   


(54) METHODS FOR THE PREVENTION AND TREATMENT OF PARASITIC INFECTIONS AND RELATED DISEASES USING CPG OLIGONUCLEOTIDES