| (84) |
Designated Contracting States: |
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AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE |
| (30) |
Priority: |
15.05.1998 US 85714 P
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| (43) |
Date of publication of application: |
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28.02.2001 Bulletin 2001/09 |
| (60) |
Divisional application: |
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07008760.6 |
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07008761.4 |
| (73) |
Proprietor: Receptor Biologix, Inc. |
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Palo Alto, California 94303 (US) |
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| (72) |
Inventors: |
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- GEVAS, Philip, C.
Key Biscayne, FL 33149 (US)
- GRIMES, Stephen
Davis, CA 95616 (US)
- KARR, Stephen
Davis, CA 95616 (US)
- MICHAELI, Dov
Larkspur, CA 94939 (US)
- WATSON, Susan
Edwalton,
Nottingham NG2 6RB (GB)
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| (74) |
Representative: Manaton, Ross Timothy et al |
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Bromhead Johnson
19 Buckingham Street London WC2N 6EF London WC2N 6EF (GB) |
| (56) |
References cited: :
WO-A-97/28821 US-A- 5 468 494 US-A- 5 609 870
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US-A- 5 023 077 US-A- 5 607 676 US-A- 5 622 702
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- WATSON SUSAN A ET AL: "Pre-clinical evaluation of the gastrimmune immunogen alone
and in combination with 5-fluorouracil/leucovorin in a rat colorectal cancer model."
INTERNATIONAL JOURNAL OF CANCER, vol. 75, no. 6, 16 March 1998 (1998-03-16), pages
873-877, XP002194963 ISSN: 0020-7136
- SUMII MASAHARU ET AL: "Regulation of antral peptides by administration of omeprazole
to healthy men." AMERICAN JOURNAL OF GASTROENTEROLOGY, vol. 89, no. 11, 1994, pages
2033-2037, XP001068668 ISSN: 0002-9270
- MCCLOY R F ET AL: "Pathophysiological effects of long-term acid suppression in man."
DIGESTIVE DISEASES AND SCIENCES, vol. 40, no. 2 SUPPL., 1995, pages 96S-120S, XP001068385
ISSN: 0163-2116
- FRESTON JAMES W: "Long-term acid control and proton pump inhibitors: Interactions
and safety issues in perspective." AMERICAN JOURNAL OF GASTROENTEROLOGY, vol. 92,
no. 4 SUPPL., 1997, pages 51S-57S, XP001068667 ISSN: 0002-9270
- REGULATORY PEPTIDES THORNDYKE M.: 'Identification and localization of material with
gastrin-like immunoreactivity in the neutral ganglion of a photochordate, Ciona intestinalis'
vol. 16, 1986, pages 269 - 279, XP002921542.
- CANCER RESEARCH WATSON ET AL: 'Gastrimmune Raises Antibodies that Neutralize Amidated
and Glycine extended Gastrin-17 and inhibit the growth of colon cancer' vol. 56, 1996,
pages 880 - 885, XP002921543.
- INT. J. CANCER WATSON ET AL: 'Anti-gastrin antibodies raised by gastrimmune inhibit
growth of the human colorectal tumor AP5' vol. 61, 1995, pages 233 - 240, XP000654518.
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