(19)
(11) EP 1 078 075 A2

(12)

(88) Date of publication A3:
17.02.2000

(43) Date of publication:
28.02.2001 Bulletin 2001/09

(21) Application number: 99924155.7

(22) Date of filing: 07.05.1999
(51) International Patent Classification (IPC)7C12N 15/56, C12N 15/85, C12N 9/24, C12N 5/00, C12N 5/10, A61K 38/47
(86) International application number:
PCT/US9910/102
(87) International publication number:
WO 9958/691 (18.11.1999 Gazette 1999/46)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

(30) Priority: 13.05.1998 US 78209
13.10.1998 US 170977

(71) Applicant: Harbor-Ucla Research and Education Institute
Torrance, CA 90920-2064 (US)

(72) Inventors:
  • KAKKIS, Emil, D.
    Long Beach, CA 90814 (US)
  • TANAMACHI, Becky
    Signal Hill, CA 90807 (US)

(74) Representative: Schüssler, Andrea, Dr. 
Kanzlei Huber & SchüsslerTruderinger Strasse 246
81825 München
81825 München (DE)

   


(54) RECOMBINANT (ALPHA)-L-IDURONIDASE, METHODS FOR PRODUCING AND PURIFYING THE SAME AND METHODS FOR TREATING DISEASES CAUSED BY DEFICIENCIES THEREOF