(19)
(11) EP 1 080 091 A1

(12)

(43) Date of publication:
07.03.2001 Bulletin 2001/10

(21) Application number: 99920561.0

(22) Date of filing: 14.05.1999
(51) International Patent Classification (IPC)7: C07D 471/10, A61K 31/445
(86) International application number:
PCT/DK9900/266
(87) International publication number:
WO 9959/997 (25.11.1999 Gazette 1999/47)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU NL PT SE

(30) Priority: 18.05.1998 DK 68198
20.05.1998 DK 71198
26.05.1998 DK 72998
10.07.1998 DK 92798
29.01.1999 DK 11199

(71) Applicant: Novo Nordisk A/S
2880 Bagsvaerd (DK)

(72) Inventors:
  • WATSON, Brett
    DK-3500 Vaerloese (DK)
  • HOHLWEG, Rolf
    DK-3490 Kvistgaard (DK)
  • THOMSEN, Christian
    DK-4671 Str by (DK)

   


(54) NOVEL 1,3,8-TRIAZASPIRO[4.5]DECANONES WITH HIGH AFFINITY FOR OPIOID RECEPTOR SUBTYPES