COMPOSITIONS AND METHODS FOR THE PULMONARY DELIVERY OF NUCLEIC ACIDS - Patent 1080225

(19)

(11)

EP 1 080 225 A1

(12)

(43)	Date of publication:
	07.03.2001 Bulletin 2001/10

(21)	Application number: 99923251.5

(22)	Date of filing: 20.05.1999

(51)	International Patent Classification (IPC)⁷: C12Q 1/68, C12N 15/00, C12N 15/85, C12N 15/63, C12N 15/11, C12P 19/34, C07H 21/04, A61K 48/00

(86)	International application number:
	PCT/US9911/141

(87)	International publication number:
	WO 9960/166 (25.11.1999 Gazette 1999/47)

(84)	Designated Contracting States:
	AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

(30)

Priority:

21.05.1998 US 83586

(71)	Applicant: ISIS PHARMACEUTICALS, INC.
	Carlsbad, CA 92008 (US)

(72)	Inventors:
	BENNETT, Clarence, Frank Carlsbad, CA 92009 (US) ECKER, David, J. Encinitas, CA 92024 (US) COOK, Phillip, Dan Fallbrook, CA 92028 (US)

(74)	Representative: Hallybone, Huw George et al
	CARPMAELS AND RANSFORD43 Bloomsbury Square London WC1A 2RA London WC1A 2RA (GB)

(54)	COMPOSITIONS AND METHODS FOR THE PULMONARY DELIVERY OF NUCLEIC ACIDS