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(11)

EP 1 080 228 A1

(12)

(43) Date of publication: 07.03.2001 Bulletin 2001/10 (21) Application number: 99924350.4 (22) Date of filing: 18.05.1999

(51) International Patent Classification (IPC)7: C12Q 1/68, C07H 21/02, C07H 21/04, C12N 15/00 (86) International application number: PCT/US9911/046 (87) International publication number: WO 9960/163 (25.11.1999 Gazette 1999/47)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE (30) Priority: 18.05.1998 US 88561 P (71) Applicant: Igenex, Inc. Palo Alto, CA 94303 (US)	(72) Inventors: SHAH, Jyotsna, S. Nashua, NH 03060 (US) HARRIS, Nick, S. Las Gatos, CA 95030 (US) (74) Representative: Holdcroft, James Gerald, Dr. et al Graham Watt & Co.3 Gray's Inn Square LondonWC1R 5AH LondonWC1R 5AH (GB)