(19)

(11)

EP 1 082 424 A1

(12)

(43) Date of publication: 14.03.2001 Bulletin 2001/11 (21) Application number: 99924381.9 (22) Date of filing: 20.05.1999

(51) International Patent Classification (IPC)7: C12N 15/12, C07K 14/47, A61K 38/17, C12Q 1/68 (86) International application number: PCT/US9911/136 (87) International publication number: WO 9961/612 (02.12.1999 Gazette 1999/48)

(84) Designated Contracting States: BE DE ES FR GB IT NL (30) Priority: 28.05.1998 US 86359 (71) Applicant: INCYTE PHARMACEUTICALS, INC. Palo Alto, CA 94304 (US)	(72) Inventors: TANG, Y., Tom San Jose, CA 95118 (US) CORLEY, Neil, C. Mountain View, CA 94040 (US) PATTERSON, Chandra Mountain View, CA 94040 (US) (74) Representative: Wright, Simon Mark et al J.A. Kemp & Co.14 South SquareGray's Inn London WC1R 5LX London WC1R 5LX (GB)