(19)
(11) EP 1 082 462 A1

(12)

(43) Date of publication:
14.03.2001 Bulletin 2001/11

(21) Application number: 99922938.8

(22) Date of filing: 12.05.1999
(51) International Patent Classification (IPC)7C12Q 1/68, A61K 48/00
(86) International application number:
PCT/US9910/343
(87) International publication number:
WO 9958/719 (18.11.1999 Gazette 1999/46)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

(30) Priority: 12.05.1998 US 85092 P
12.05.1998 US 76440

(71) Applicant: ISIS PHARMACEUTICALS, INC.
Carlsbad, CA 92008 (US)

(72) Inventors:
  • ECKER, David, J.
    Encinitas, CA 92024 (US)
  • SAMPATH, Ranga
    San Diego, CA 92129 (US)
  • GRIFFEY, Richard
    Vista, CA 92084 (US)
  • MCNEIL, John
    La Jolla, CA 92037 (US)

(74) Representative: Hallybone, Huw George et al
CARPMAELS AND RANSFORD43 Bloomsbury Square
London WC1A 2RA
London WC1A 2RA (GB)

   


(54) IDENTIFICATION OF MOLECULAR INTERACTION SITES IN RNA FOR NOVEL DRUG DISCOVERY