(19)

(11)

EP 1 084 247 A1

(12)

(43) Date of publication: 21.03.2001 Bulletin 2001/12 (21) Application number: 99927247.9 (22) Date of filing: 04.06.1999

(51) International Patent Classification (IPC)7: C12N 15/15, C07K 14/81, C07K 16/38, C07K 16/42 (86) International application number: PCT/US9912/545 (87) International publication number: WO 9963/091 (09.12.1999 Gazette 1999/49)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE (30) Priority: 04.06.1998 US 90895 (71) Applicant: ZymoGenetics, Inc. Seattle, WA 98102 (US)	(72) Inventor: CONKLIN, Darrell C.,Apartment 2 Seattle, WA 98102 (US) (74) Representative: Schlich, George William et al Mathys & Squire100 Gray's Inn Road London WC1X 8AL London WC1X 8AL (GB)