(19)
(11) EP 1 084 261 B8

(12) CORRECTED EUROPEAN PATENT SPECIFICATION
Note: Bibliography reflects the latest situation

(15) Correction information:
Corrected version no 1 (W1 B1)

(48) Corrigendum issued on:
15.12.2004 Bulletin 2004/51

(45) Mention of the grant of the patent:
08.09.2004 Bulletin 2004/37

(21) Application number: 99920967.9

(22) Date of filing: 05.05.1999
(51) International Patent Classification (IPC)7: C12N 15/63, A61K 39/12, A61K 39/295
(86) International application number:
PCT/GB1999/001387
(87) International publication number:
WO 1999/063098 (09.12.1999 Gazette 1999/49)

(54)

RECOMBINANT VENEZUELAN EQUINE ENCEPHALITIS VIRUS VACCINE

REKOMBINANTER VENEZOLANISCHE-EQUINE-PFERDEENZEPHALITIS-VIRUSIMPSTOFF

VACCIN ANTIVIRAL RECOMBINANT DE L'ENCEPHALITE EQUINE DU VENEZUELA

(84) Designated Contracting States:
AT BE CH DE DK ES FI FR GB IE IT LI LU NL PT SE

(30) Priority: 29.05.1998 GB 9811433

(43) Date of publication of application:
21.03.2001 Bulletin 2001/12

(73) Proprietor: The Secretary of State for Defence
Salisbury SP4 0JQ (GB)

(72) Inventor:
  • BENNETT, Alice Marie
    Salisbury, Wiltshire SP4 0JQ (GB)

(74) Representative: Beckham, Robert William et al
D/IPR Formalities Section, Poplar 2, MOD Abbey Wood #2218
Bristol BS34 8JH
Bristol BS34 8JH (GB)


(56) References cited: : 
US-A- 5 185 440
   
  • KINNEY R M ET AL: "Recombinant vaccinia/Venezuelan equine encephalitis ( VEE ) virus expresses VEE structural proteins." JOURNAL OF GENERAL VIROLOGY, (1988 DEC) 69 ( PT 12) 3005-13. , XP002118353 cited in the application
  • DAVISON, ANDREW J. ET AL: "Structure of vaccinia virus early promoters" J. MOL. BIOL. (1989), 210(4), 749-69 , XP002118354
  • KINNEY R M ET AL: "The full-length nucleotide sequences of the virulent Trinidad donkey strain of Venezuelan equine encephalitis virus and its attenuated vaccine derivative, strain TC-83." VIROLOGY, (1989 MAY) 170 (1) 19-30. , XP002117670
  • HUNT A R ET AL: "Localization of a protective epitope on a Venezuelan equine encephalomyelitis ( VEE ) virus peptide that protects mice from both epizootic and enzootic VEE virus challenge and is immunogenic in horses." VACCINE, (1995 FEB) 13 (3) 281-8. , XP004057668 cited in the application
  • AGAPOV E V ET AL: "Localization of four antigenic sites involved in Venezuelan equine encephalomyelitis virus protection." ARCHIVES OF VIROLOGY, (1994) 139 (1-2) 173-81. , XP002117671
  • BENNETT A M ET AL: "Improved protection against Venezuelan equine encephalitis by genetic engineering of a recombinant vaccinia virus." VIRAL IMMUNOLOGY, (1998) 11 (3) 109-17. , XP002117672
   
Note: Within nine months from the publication of the mention of the grant of the European patent, any person may give notice to the European Patent Office of opposition to the European patent granted. Notice of opposition shall be filed in a written reasoned statement. It shall not be deemed to have been filed until the opposition fee has been paid. (Art. 99(1) European Patent Convention).