(19)

(11)

EP 1 086 064 A2

(12)

(88) Date of publication A3: 21.09.2000 (43) Date of publication: 28.03.2001 Bulletin 2001/13 (21) Application number: 99927613.2 (22) Date of filing: 10.06.1999

(51) International Patent Classification (IPC)7: C07B 61/00, C07K 9/00, C07H 19/06, C07H 19/16, C12Q 1/48, A61K 38/14 (86) International application number: PCT/CA9900/550 (87) International publication number: WO 9964/378 (16.12.1999 Gazette 1999/50)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE (30) Priority: 10.06.1998 US 88828 P 17.02.1999 US 120562 P (71) Applicant: Glycodesign Inc. Toronto,Ontario M5G 1V2 (CA)

(72) Inventors: CARVER, Jeremy Toronto,Ontario M4W 1Z2 (CA) DENNIS, James Etobicoke, Ontario M9C 2V7 (CA) TROPPER, François D. North York,Ontario M3B 2V7 (CA) SAHA, Uttam North York, Ontario M9N 2R4 (CA) ZISER, Lothar Toronto, Ontario M5B 2H5 (CA) DATTI, Alessandro Toronto, Ontario M5S 3A6 (CA) DONOVAN, Rob Willowdale,Ontario M2R 3V4 (CA) (74) Representative: Harding, Charles Thomas et al D. Young & Co.21 New Fetter Lane London EC4A 1DA London EC4A 1DA (GB)