(19)
(11)
EP 1 086 116 A1
(12)
(43)
Date of publication:
28.03.2001
Bulletin 2001/13
(21)
Application number:
99923263.0
(22)
Date of filing:
20.05.1999
(51)
International Patent Classification (IPC)
7
:
C07H
21/04
,
A61K
48/00
(86)
International application number:
PCT/US9911/214
(87)
International publication number:
WO 9960/010
(
25.11.1999
Gazette 1999/47)
(84)
Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
(30)
Priority:
21.05.1998
US 83585
(71)
Applicant:
ISIS PHARMACEUTICALS, INC.
Carlsbad, CA 92008 (US)
(72)
Inventors:
BENNETT, Clarence, Frank
Carlsbad, CA 92009 (US)
ECKER, David, J.
Encinitas, CA 92024 (US)
COOK, Phillip, Dan
Fallbrook, CA 92028 (US)
(74)
Representative:
Hallybone, Huw George
CARPMAELS AND RANSFORD43 Bloomsbury Square
London WC1A 2RA
London WC1A 2RA (GB)
(54)
COMPOSITIONS AND METHODS FOR THE PULMONARY DELIVERY OF NUCLEIC ACIDS