(19)

(11)

EP 1 086 222 A2

(12)

(88) Date of publication A3: 30.03.2000 (43) Date of publication: 28.03.2001 Bulletin 2001/13 (21) Application number: 99933509.4 (22) Date of filing: 08.06.1999

(51) International Patent Classification (IPC)7: C12N 15/12, C12N 5/10, C12N 1/21, C07K 14/47, C07K 16/18, C12Q 1/68, A61K 38/17 (86) International application number: PCT/US9912/906 (87) International publication number: WO 9964/593 (16.12.1999 Gazette 1999/50)

(84) Designated Contracting States: BE DE ES FR GB IT NL (30) Priority: 08.06.1998 US 88695 P (71) Applicant: INCYTE PHARMACEUTICALS, INC. Palo Alto, CA 94304 (US)

(72) Inventors: BANDMAN, Olga Mountain View, CA 94043 (US) LAL, Preeti Santa Clara, CA 95054 (US) TANG, Y., Tom San Jose, CA 95118 (US) CORLEY, Neil, C. Mountain View, CA 94040 (US) GUEGLER, Karl, J. Menlo Park, CA 94025 (US) BAUGHN, Mariah, R. San Leandro, CA 94577 (US) PATTERSON, Chandra Menlo Park, CA 94025 (US) (74) Representative: Wright, Simon Mark  J.A. Kemp & Co.14 South SquareGray's Inn London WC1R 5LX London WC1R 5LX (GB)