(19)

(11)

EP 1 086 234 A1

(12)

(43) Date of publication: 28.03.2001 Bulletin 2001/13 (21) Application number: 98926512.9 (22) Date of filing: 10.06.1998

(51) International Patent Classification (IPC)7: C12N 15/57, C07K 14/81, C07K 16/38, C12Q 1/68 (86) International application number: PCT/US9812/020 (87) International publication number: WO 9964/609 (16.12.1999 Gazette 1999/50)

(84) Designated Contracting States: BE DE ES FR GB IT NL (71) Applicant: INCYTE PHARMACEUTICALS, INC. Palo Alto, CA 94304 (US)	(72) Inventors: HILLMAN, Jennifer, L. Mountain View, CA 94034 (US) LAL, Preeti Santa Clara, CA 95054 (US) (74) Representative: Wright, Simon Mark et al J.A. Kemp & Co.14 South SquareGray's Inn London WC1R 5LX London WC1R 5LX (GB)