(19)

(11)

EP 1 086 242 A1

(12)

(43) Date of publication: 28.03.2001 Bulletin 2001/13 (21) Application number: 99942591.1 (22) Date of filing: 22.03.1999

(51) International Patent Classification (IPC)7: C12Q 1/533, G01N 33/58 (86) International application number: PCT/IB9900/473 (87) International publication number: WO 9949/077 (30.09.1999 Gazette 1999/39)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU NL PT SE (30) Priority: 25.03.1998 US 79265 P (71) Applicant: The Procter & Gamble Company Cincinnati,Ohio 45202 (US)	(72) Inventors: CATRENICH, Carl, Edward Fairfield, OH 45014 (US) MAKIN, Kelly, Maureen West Harrison, IN 47060 (US) (74) Representative: Clemo, Nicholas Graham et al Patent Department,Procter & Gamble Technical Centres Limited,Rusham Park,Whitehall Lane Egham, Surrey TW20 9NW Egham, Surrey TW20 9NW (GB)