(19)

(11)

EP 1 086 494 A1

(12)

(43) Date of publication: 28.03.2001 Bulletin 2001/13 (21) Application number: 99924222.5 (22) Date of filing: 14.05.1999

(51) International Patent Classification (IPC)7: H01L 29/04, G01N 7/00, G01N 25/18, G01N 25/08, G01N 27/416, G01N 1/18, G01N 21/62 (86) International application number: PCT/US9910/579 (87) International publication number: WO 9960/630 (25.11.1999 Gazette 1999/47)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE (30) Priority: 15.05.1998 US 85736 P (71) Applicant: GLAXO GROUP LIMITED Greenford, Middlesex UB6 ONN (GB)	(72) Inventors: LENHARD, James Martin,Glaxo Wellcome Inc. Research Triangle Park, NC 27709 (US) PAULIK, Mark Andrew,Glaxo Wellcome Inc. Research Triangle Park, NC 27709 (US) (74) Representative: Dawson, Hugh Bainforde  Glaxo Wellcome plcGlaxo Wellcome House,Berkeley Avenue GreenfordMiddlesex UB6 0NN GreenfordMiddlesex UB6 0NN (GB)