(19)

(11)

EP 1 088 068 A1

(12)

(43) Date of publication: 04.04.2001 Bulletin 2001/14 (21) Application number: 99925747.0 (22) Date of filing: 20.05.1999

(51) International Patent Classification (IPC)7: C12N 15/12, C12N 15/62, C12N 5/10, C12N 1/19, C07K 14/705, C07K 16/28 // C12N1:19, C12R1:84 (86) International application number: PCT/US9911/337 (87) International publication number: WO 9966/040 (23.12.1999 Gazette 1999/51)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE (30) Priority: 18.06.1998 US 99600 (71) Applicant: ZymoGenetics, Inc. Seattle, WA 98102 (US)	(72) Inventor: SHEPPARD, Paul, O. Redmond, WA 98053 (US) (74) Representative: Schlich, George William et al Mathys & Squire100 Gray's Inn Road London WC1X 8AL London WC1X 8AL (GB)