(19)
(11) EP 1 089 715 B8

(12) CORRECTED EUROPEAN PATENT SPECIFICATION
Note: Bibliography reflects the latest situation

(15) Correction information:
Corrected version no 1 (W1 B1)

(48) Corrigendum issued on:
01.02.2006 Bulletin 2006/05

(45) Mention of the grant of the patent:
30.11.2005 Bulletin 2005/48

(21) Application number: 99930689.7

(22) Date of filing: 24.06.1999
(51) International Patent Classification (IPC): 
A61K 9/12(1974.07)
A61K 31/58(1985.01)
 A61K 31/56(1985.01)
(86) International application number:
PCT/US1999/014351
(87) International publication number:
WO 2000/000181 (06.01.2000 Gazette 2000/01)

(54)

AQUEOUS COMPOSITIONS CONTAINING CORTICOSTEROIDS FOR NASAL AND PULMONARY DELIVERY

WÄSSRIGE ZUSAMMENSTELLUNGEN DIE CORTICOSTEROIDE ENTHALTEN ZUR NASALEN ODER PULMONALEN VERABREICHUNG

COMPOSITIONS AQUEUSES CONTENANT DES CORTICOSTEROIDES ET DESTINEES A L'ADMINISTRATION NASALE ET PULMONAIRE

(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

(30) Priority: 26.06.1998 US 105838

(43) Date of publication of application:
11.04.2001 Bulletin 2001/15

(73) Proprietor: ATHENA NEUROSCIENCES, INC.
South San Francisco, CA 94080 (US)

(72) Inventors:
  • SAIDI, Zahir
    Philadelphia, PA 19147 (US)
  • KLYASHCHITSKY, Boris
    Newark, DE 19702 (US)

(74) Representative: W.P. Thompson & Co. 
Eastcheap House Central Approach
Letchworth Garden City, Hertfordshire SG6 3DS
Letchworth Garden City, Hertfordshire SG6 3DS (GB)


(56) References cited: : 
WO-A-95/31964
US-A- 4 782 047
 US-A- 4 567 161
US-A- 5 478 860
   
  • ADAMS M W: "D-ALPHA TOCOPHERYL POLYETHYLENE GLYCOL 1000 SUCCINATE (EASTMAN VITAMI E TPGS) AS AN EMULSIFIER AND BIOENHANCER FOR DRUGS AND LIPOPHILIC COMPOUNDS" INTERNATIONAL CONGRESS OF TECHNOLOGY AND PHARMACOLOGY, ASSOC. PHARM. GALENIQUE IND., CHATENAY MALABRY, FR, 1992, pages 254-262, XP000576964
  • DATABASE WPI Section Ch, Derwent Publications Ltd., London, GB; Class B00, AN 1966-34886F XP002266494 & JP 43 025567 B (YAMANOUCHI PHARM CO LTD)
  • LY J. et al., "Evaluation and Application of Hydrophilic Tocopherol Polyethylene Glycol Derivatives as Enhancers of Drug Solubility"; In: COLLEGE OF PHARMACY AND ALLIED HEALTH PROFESSIONS, St. JOHN'S UNIVERSITY, JAMAICA, NY, Presentation ID: 3419, 05 November 1997, 1 page Summary.
   
Note: Within nine months from the publication of the mention of the grant of the European patent, any person may give notice to the European Patent Office of opposition to the European patent granted. Notice of opposition shall be filed in a written reasoned statement. It shall not be deemed to have been filed until the opposition fee has been paid. (Art. 99(1) European Patent Convention).