(19)
(11) EP 1 089 990 A1

(12)

(43) Date of publication:
11.04.2001 Bulletin 2001/15

(21) Application number: 99931915.5

(22) Date of filing: 25.06.1999
(51) International Patent Classification (IPC)7C07D 277/82, C07D 277/68
// A61K31:495
(86) International application number:
PCT/US9914/427
(87) International publication number:
WO 0000/482 (06.01.2000 Gazette 2000/01)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
Designated Extension States:
AL LT LV MK RO SI

(30) Priority: 30.06.1998 US 107607

(71) Applicant: NEUROGEN CORPORATION
Branford, CT 06405 (US)

(72) Inventor:
  • CHEN, Xi
    Killingworth, CT 06719 (US)

(74) Representative: Smaggasgale, Gillian 
W.P. Thompson & Co,Celcon House,289-293 High Holborn
London WC1V 7HU
London WC1V 7HU (GB)

   


(54) 1-(BENZOTHIAZOL-2-YL)-4-(1-PHENYLMETHYL)PIPERAZINES: DOPAMINE RECEPTOR SUBTYPE SPECIFIC LIGANDS