6-(4-ARYLALKYLPIPERAZIN-1-YL)BENZODIOXANE AND 6-(4-ARYLALKYLPIPERAZIN-1-YL)CHROMANE DERIVATIVES: DOPAMINE RECEPTOR SUBTYPE SPECIFIC LIGANDS - Patent 1091949

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(11)

EP 1 091 949 A2

(12)

(88)	Date of publication A3:
	10.02.2000

(43)	Date of publication:
	18.04.2001 Bulletin 2001/16

(21)	Application number: 99930727.5

(22)	Date of filing: 25.06.1999

(51)	International Patent Classification (IPC)⁷: C07D 311/04, C07D 307/79, C07D 319/18, C07D 321/10, C07D 313/08, C07D 405/04

(86)	International application number:
	PCT/US9914/426

(87)	International publication number:
	WO 0000/489 (06.01.2000 Gazette 2000/01)

(84)	Designated Contracting States:
	AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
	Designated Extension States:
	AL LT LV MK RO SI

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Priority:

30.06.1998 US 109242

(71)	Applicant: NEUROGEN CORPORATION
	Branford, CT 06405 (US)

(72)	Inventors:
	TRAN, Jennifer, N. Guilford, CT 06437 (US) THURKAUF, Andrew Danbury, CT 06811 (US)

(74)	Representative: W.P. THOMPSON & CO.
	Celcon House289-293 High Holborn London WC1V 7HU London WC1V 7HU (GB)

(54)	6-(4-ARYLALKYLPIPERAZIN-1-YL)BENZODIOXANE AND 6-(4-ARYLALKYLPIPERAZIN-1-YL)CHROMANE DERIVATIVES: DOPAMINE RECEPTOR SUBTYPE SPECIFIC LIGANDS