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(11)

EP 1 093 523 A1

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(43) Date of publication: 25.04.2001 Bulletin 2001/17 (21) Application number: 00931950.0 (22) Date of filing: 25.04.2000

(51) International Patent Classification (IPC)7: C12N 15/82, C07K 14/415, C12N 5/14, C12N 15/63 (86) International application number: PCT/US0011/086 (87) International publication number: WO 0068/404 (16.11.2000 Gazette 2000/46)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE Designated Extension States: AL LT LV MK RO SI (30) Priority: 05.05.1999 US 132575 P (71) Applicant: PIONEER HI-BRED INTERNATIONAL, INC. Des Moines, Iowa 50309 (US)	(72) Inventors: MAHAJAN, Pramod, B. Urbandale, IA 50022 (US) SHI, Jinrui Johnston, IA 50131 (US) (74) Representative: Goldin, Douglas Michael  J.A. KEMP & CO.14 South SquareGray's Inn London WC1R 5LX London WC1R 5LX (GB)