METHODS FOR ACCELERATING BONE AND CARTILAGE GROWTH AND REPAIR

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EP 1 094 829 B8

(12)	CORRECTED EUROPEAN PATENT SPECIFICATION
	Note: Bibliography reflects the latest situation

(15)	Correction information:
	Corrected version no 1 (W1 B1)

(48)	Corrigendum issued on:
	22.09.2004 Bulletin 2004/39

(45)	Mention of the grant of the patent:
	24.09.2003 Bulletin 2003/39

(21)	Application number: 99933921.1

(22)	Date of filing: 12.07.1999

(51)	International Patent Classification (IPC)⁷: A61K 38/08, C07K 7/14, C12N 5/06

(86)	International application number:
	PCT/US1999/015735

(87)	International publication number:
	WO 2000/002905 (20.01.2000 Gazette 2000/03)

(54)	METHODS FOR ACCELERATING BONE AND CARTILAGE GROWTH AND REPAIR VERFAHREN ZUR BESCHLEUNIGUNG VON KNOCHEN- UND KNORPELWACHSTUM UND REPARATUR PROCEDES PERMETTANT D'ACCELERER LA REPARATION ET LA CROISSANCE DES OS ET DES CARTILAGES

(84)	Designated Contracting States:
	AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

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Priority:

13.07.1998 US 92653 P
22.04.1999 US 130855 P

(43)	Date of publication of application:
	02.05.2001 Bulletin 2001/18

(73)	Proprietor: UNIVERSITY OF SOUTHERN CALIFORNIA
	Los Angeles, CA 90007-4344 (US)

(72)	Inventors:
	RODGERS, Kathleen Long Beach, CA 90815 (US) DIZEREGA, Gere Pasadena, CA 91106 (US)

(74)	Representative: Grund, Martin, Dr. et al
	Dr. Volker Vossius, Patentanwaltskanzlei, Geibelstrasse 6 81679 München 81679 München (DE)

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References cited: :

WO-A-96/14858
WO-A-99/46285

WO-A-96/39164

DATABASE CHEMABS [Online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US HAGIWARA, MITSUHIDE ET AL.: "Regulation of bone metabolism by vasoactive peptides" retrieved from STN FILE CA Database accession no. 129:36502 XP002900711 & SAISHIN IGAKU, vol. 53, no. 6, 1998, pages 1289-1294, ISSN: 0370-8241
DATABASE MEDLINE [Online] US NATIONAL LIBRARY OF MEDICINE (NLM), BETHESDA, MD, US LAMPARTER, S. ET AL.: "Effects of angiotensin II on bone cells in vitro" retrieved from MEDLINE, accession no. 1998150748 XP002900712 & JOURNAL OF CELLULAR PHYSIOLOGY, vol. 175, no. 1, April 1998 (1998-04), pages 89-98, ISSN: 0021-9541
DATABASE CHEMABS [Online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US HATTON, R. ET AL.: "Angiotensin II is generated from angiotensin I by bone cells and stimulates osteoclastic bone resorption in vitro" retrieved from STN, accession no. 127:1149 XP002900713 & J. ENDOCRINOL., vol. 152, no. 1, 1997, pages 84x5-10, ISSN: 0022-0795

Note: Within nine months from the publication of the mention of the grant of the European patent, any person may give notice to the European Patent Office of opposition to the European patent granted. Notice of opposition shall be filed in a written reasoned statement. It shall not be deemed to have been filed until the opposition fee has been paid. (Art. 99(1) European Patent Convention).