(19)

(11)

EP 1 097 219 A2

(12)

(88) Date of publication A3: 22.06.2000 (43) Date of publication: 09.05.2001 Bulletin 2001/19 (21) Application number: 99934112.6 (22) Date of filing: 16.07.1999

(51) International Patent Classification (IPC)7: C12N 15/53, C12N 9/02, C12N 5/10, A61K 48/00, C12Q 1/68, C07K 16/28 (86) International application number: PCT/US9916/164 (87) International publication number: WO 0004/135 (27.01.2000 Gazette 2000/04)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE Designated Extension States: AL LT LV MK RO SI (30) Priority: 16.07.1998 US 116750 16.07.1998 US 160074 P (71) Applicant: INCYTE PHARMACEUTICALS, INC. Palo Alto, CA 94304 (US)	(72) Inventors: BANDMAN, Olga Mountain View, CA 94043 (US) TANG, Y., Tom San Jose, CA 95118 (US) CORLEY, Neil, C. Mountain View, CA 94040 (US) AZIMZAI, Yalda Hayward, CA 94547 (US) BAUGHN, Mariah, R. San Leandro, CA 94577 (US) (74) Representative: Wright, Simon Mark  J.A. Kemp & Co.14 South SquareGray's Inn London WC1R 5LX London WC1R 5LX (GB)