FERMENTATION PROCESS TO PRODUCE CLAVULANIC ACID AT A LOW CONCENTRATION OF FREE AMINO ACIDS - Patent 1097238

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EP 1 097 238 A1

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(43)	Date of publication:
	09.05.2001 Bulletin 2001/19

(21)	Application number: 99939986.8

(22)	Date of filing: 01.07.1999

(51)	International Patent Classification (IPC)⁷: C12P 17/18, A61K 31/43, C12N 1/20, C07D 503/00

(86)	International application number:
	PCT/EP9904/702

(87)	International publication number:
	WO 0001/840 (13.01.2000 Gazette 2000/02)

(84)	Designated Contracting States:
	AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
	Designated Extension States:
	AL LT LV MK RO SI

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Priority:

03.07.1998 EP 98202264

(71)	Applicant: DSM N.V.
	6411 TE Heerlen (NL)

(72)	Inventors:
	DE LAAT, Wilhelmus, Theodorus, Antonius, Maria NL-4817 KW Breda (NL) KRABBEN, Preben NL-2624 KL Delft (NL)

(74)	Representative: Matulewicz, Emil Rudolf Antonius et al
	DSM- Patents & Trademarks (994-0760),P.O. Box 1 2600 MA Delft 2600 MA Delft (NL)

(54)	FERMENTATION PROCESS TO PRODUCE CLAVULANIC ACID AT A LOW CONCENTRATION OF FREE AMINO ACIDS