(19)

(11)

EP 1 100 438 A1

(12)

(43) Date of publication: 23.05.2001 Bulletin 2001/21 (21) Application number: 99914962.8 (22) Date of filing: 26.03.1999

(51) International Patent Classification (IPC)7: A61K 7/06 (86) International application number: PCT/US9906/114 (87) International publication number: WO 0006/102 (10.02.2000 Gazette 2000/06)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU NL PT SE (30) Priority: 30.07.1998 WO PCT/US98/15749 (71) Applicant: THE PROCTER & GAMBLE COMPANY Cincinnati,Ohio 45202 (US)

(72) Inventors: McCANN, Chantelle Mary Egham,Surrey TW20 8BN (GB) McMEEKIN, Anthony Chertsey,Surrey KT16 9HW (GB) McKELVEY, Graham Neil Woking,Surrey GU21 2AR (GB) YOUNG, Wendy Victoria Jane Nr Newbury,Berkshire RG14 2TA (GB) (74) Representative: Kohol, Sonia et al Patent Department,Procter & Gamble Technical Centres Limited,Rusham Park,Whitehall Lane Egham,Surrey TW20 9NW Egham,Surrey TW20 9NW (GB)