(19)

(11)

EP 1 102 582 A2

(12)

(88) Date of publication A3: 30.03.2000 (43) Date of publication: 30.05.2001 Bulletin 2001/22 (21) Application number: 99936218.9 (22) Date of filing: 06.08.1999

(51) International Patent Classification (IPC)7: A61K 31/00, A61K 31/565, A61K 31/566, A61K 31/567, A61K 31/585, A61K 45/06, A61P 35/00, A61P 17/10, A61P 17/08, A61P 17/14, A61P 5/26 (86) International application number: PCT/CA9900/724 (87) International publication number: WO 0007/576 (17.02.2000 Gazette 2000/07)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE Designated Extension States: AL LT LV MK RO SI (30) Priority: 07.08.1998 US 95623 P (71) Applicant: Endorecherche Inc. Sainte-Foy,Quebec G1W 2J5 (CA)	(72) Inventors: LABRIE, Fernand Ste-Foy, Québec G1W 2J5 (CA) MERAND, Yves Sainte-Foy, Québec G1W 3A1 (CA) GAUTHIER, Sylvain Saint-Augustin-de-Desmaures, Québec G3A (CA) PROVENCHER, Louis Charny, Québec G6X 3R7 (CA) LUU-THE, Van Charny, Québec G6X 1C6 (CA) (74) Representative: Larfeldt, Helene et al Bergensträhle & Lindvall ABP.O. Box 17704 118 93 Stockholm 118 93 Stockholm (SE)