(19)
(11) EP 1 102 842 A2

(12)

(88) Date of publication A3:
18.05.2000

(43) Date of publication:
30.05.2001 Bulletin 2001/22

(21) Application number: 99938373.0

(22) Date of filing: 29.07.1999
(51) International Patent Classification (IPC)7: C12N 15/11, A61K 31/70, C07H 21/00
// (A61P9/00, 35:00)
(86) International application number:
PCT/EP9905/432
(87) International publication number:
WO 0008/140 (17.02.2000 Gazette 2000/07)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
Designated Extension States:
AL LT LV MK RO SI

(30) Priority: 07.08.1998 EP 98114854

(71) Applicant: Aventis Pharma Deutschland GmbH
65929 Frankfurt am Main (DE)

(72) Inventors:
  • UHLMANN, Eugen
    D-61479 Glashütten (DE)
  • PEYMAN, Anuschirwan
    D-65779 Kelkheim (DE)
  • BITONTI, Alan
    Ringoes, NJ 08551 (US)
  • WOESSNER, Richard
    Lebanon, NJ 08833 (US)

   


(54) ANTISENSE OLIGONUCLEOTIDES FOR THE INHIBITION OF VEGF EXPRESSION